KARDIA was developed in Matlab programming language and runs on

recent Matlab releases (2007 or later) on all supported operating systems

(Mac OS X, Unix and Windows). KARDIA allows interactive importing

and visualization of both IBI data and event-related information. Available

functions permit the analysis of phasic heart rate changes in response to

specific visual or auditory stimuli, using either weighted averages or

different interpolation methods (constant, linear, spline) at any user-defined analysis window or sampling rate. KARDIA also provides the user

with functions to calculate all commonly used time-domain statistics of

heart rate variability and to perform spectral decomposition by using either

Fast Fourier Transform or auto-regressive models. Scaling properties of

the IBI series can also be assessed by means of Detrended Fluctuation

Analysis. Quantitative results can be easily exported in Excel and Matlab

format for further statistical analysis.