关联度计算的预处理，一般初值化或者均值化，本程序中使用的是比较序列与参考序列组成的矩阵除以参考序列的列均值等到的(The preprocessing of the degree of association calculation, generally initialization or averaging, in this procedure is to compare the sequence and the reference sequence of the matrix, divided by the reference sequence of the column mean wait until)